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Besides being an HDAC inhibitor, microbial butyrate differentially inhibits glucose transport, glycolysis, and DNA synthesis in cancerous colonocytes via inhibiting GLUT1 and glucose-6-phosphate dehydrogenase (G6PD) through the GPR109a-AKT pathway (Geng et al., 2021)

People with severe kidney disease should watch their potassium intake

Beyond well-known interventions (such as dietary modifications), novel therapeutics (such as small interfering RNA gene silencers, recombinant oxalate-degrading enzymes and oxalate-degrading bacterial strains) hold promise to improve the outlook of patients with oxalate-related diseases

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The extracts were concentrated, and the dried matter was then dissolved in 50 mL methanol