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Any findings referenced are derived from experimental models and controlled research settings and should not be interpreted as therapeutic or clinical outcomes

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PMC 1034789

Advances in Glutathione Research for Disease Research Targeted therapy for GSH metabolism has become a research hotspot, and metabolomics and proteomics technologies have also provided powerful tools for GSH-related research: Targeting GSH metabolism : Inhibiting key molecules such as GCLC, xCT (cysteine uptake carrier) or SLC25A39 (mitochondrial GSH transporter), or using GSH-depleting nanozymes, has shown the potential to enhance ROS-mediated tumor cell death and improve related disease symptoms in preclinical models (such as cell models and animal models), providing new strategies for disease treatment

Ferroptosis may be involved in the formation of NETs and the regulation of neutrophil recruitment (102)

T.JamesG.MideiM.HeerinckxF.AtwalP.MilnerP.et al (2020)