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Predictors associated with the rate of progression of nigrostriatal degeneration in Parkinsons disease

The human body regulates iron from non-heme sources better, which is actually a good thing, considering that high iron levels can increase cardiovascular disease by increasing activity of LDL (the bad cholesterol) as well as damage the gut lining

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Front Neurosci 12:214 Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A, Eggenhofer E, Basavarajappa D, Radmark O, Kobayashi S, Seibt T, Beck H, Neff F, Esposito I, Wanke R, Forster H, Yefremova O, Heinrichmeyer M, Bornkamm GW, Geissler EK, Thomas SB, Stockwell BR, O'Donnell VB, Kagan VE, Schick JA, Conrad M (2014) Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

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Pinkard et al