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Many of these molecules can activate receptors on the vagus nerve or cross the BBB to act in the brain

doi: 10.1038/s41388-018-0315-z [DOI] [PMC free article] [PubMed] [Google Scholar] 25.Florance I, Cordani M, Pashootan P, Moosavi MA, Zarrabi A, Chandrasekaran N

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Your gut microbiome also produces neurotransmitters and hormones that influence your circadian rhythm, such as serotonin for regulating sleep and mood, and melatonin for regulating the sleep-wake cycle

Also, urinary excretion of the paracellular permeability marker chromium ethylenediamine-tetraacetic acid (CrEDTA) was not increased in comparison with infected rats fed the control diet

Oyster (Ostrea plicatula Gmelin) polysaccharides intervention ameliorates cyclophosphamide-induced genotoxicity and hepatotoxicity in mice via the Nrf2-ARE pathway