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The matched code is the closest available option, but it may not fully capture the original diagnosis or clinical intent

"Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist." JCI Insight , 5(17), e140532

Practical Takeaways If youre deciding between the three forms, heres how Id frame it: The mechanism of action is identical across all three

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Patient Selection & Clinical Decision-Making When orforglipron reaches the market, clinicians will face a new decision matrix: which GLP-1 therapy, among a growing array of options, best fits each individual patient

Multiple layers of oversight create accountability that protects patients