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doi: 10.1126/scitranslmed.aal4712 132 ArasaJCollado-DiazVKritikosIMedina-SanchezJDFriessMCSigmundECet al

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ITC-amine conjugates, such as ITC-Lys, may be more stable than GSH conjugates 47 , which are known to break down under physiological conditions, especially in the presence of free thiols 46

Western blot analysis was used to assess the expression levels of Keap-1, Nrf2, NQO1, and GPX4, revealing SAC protective effects against HO-induced oxidative stress in IEC-6 (Fig