Diwakar and Ravindranath, 2007
But the mechanism most people miss is oxidation, not just temperature
It also keeps the bodys glutathione and other antioxidants in check
Town M, Jean G, Cherqui S, Attard M, Forestier L, Whitmore SA, Callen DF, Gribouval O, Broyer M, Bates GP, vant Hoff W, Antignac C (1998) A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis
In such a way, faster recovery is supported
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Abbreviations GABA: Gamma-aminobutyric acid NMDA: N-methyl-D-aspartate HPA: Hypothalamicpituitaryadrenal AUDs: Alcohol use disorders MDD: Major depressive disorder CBT: Cognitive-behavioral therapy IL-6: Interleukin-6 TNF-: Tumor necrosis factor-alpha CRH: Corticotropin-releasing hormone ACTH: Adrenocorticotropic hormone MRI: Magnetic resonance imaging PET: Positron emission tomography SSRIs: Selective serotonin reuptake inhibitors ROS: Reactive oxygen species ADH: Alcohol dehydrogenase ALDH: Aldehyde dehydrogenase SOD: Superoxide dismutase NF-B: Nuclear factor kappa B IL-1: Interleukin-1 beta LTP: Long-term potentiation LTD: Long-term depression NLRP3: NOD-like receptor family pyrin domain containing 3 BBB: Bloodbrain barrier BDNF: Brain-derived neurotrophic factor JNK: C-Jun N-terminal kinase P38 MAPK: P38 mitogen-activated protein kinase MAPK: Mitogen-activated protein kinase CREB: CAMP response element-binding protein ERK: Extracellular signal-regulated kinase NGF: Nerve growth factor NT-3: Neurotrophin-3 SCFAs: Short-chain fatty acids FasL: Fas ligand DISC: Death-inducing signaling complex ER: Endoplasmic reticulum UPR: Unfolded protein response CHOP: C/EBP homologous protein AMPA: Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid CaMKII: Calcium/calmodulin-dependent protein kinase II PTSD: Post-traumatic stress disorder fMRI: Functional magnetic resonance imaging NE: Norepinephrine References Adams C, Conigrave JH, Lewohl J, Haber P, Morley KC (2020) Alcohol use disorder and circulating cytokines: a systematic review and meta-analysis
