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[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Bertout JA, Majmundar AJ, Gordan JD, et al

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We first outline the core molecular machinery of ferroptosis, focusing on the interplay between iron homeostasis, lipid peroxidation, the GPX4glutathione axis, and recently identified defense pathways

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RHADS generally appears in the early stages of AHS and is not affected by anti-seizure medications (ASMs)

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In DBA/2 J mice, increased levels of mitochondria with altered morphology and diminished capacity for oxidative metabolism, together with decreased LAMP1, despite increased numbers of autophagosomes, led to the belief that these mice had impaired mitophagy (Coughlin et al., 2015)

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Historical Background Methylene blue was first synthesized in 1876 by the chemist Heinrich Caro, marking the advent of synthetic drugs

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