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As the C-terminal fragment of human Growth Hormone residues 176191 with an N-terminal tyrosine addition, this compound provides researchers with a focused tool for investigating the metabolic arm of GH signalling independently of the growth-promoting and IGF-1-stimulating effects associated with the full GH molecule

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IGF-1 possesses both, GH-like actions and insulin-like actions, whose effects in vivo depend on the dosage, length of treatment, and even route of administration [134, 135]