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Tgf is essential for cartilage development, and its suppression has been correlated with decreased fetal chondrocyte proliferation and extracellular matrix content, both of which predispose individuals to osteoarthritis in adulthood

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[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Ichikawa J., Tsuchimoto D., Oka S., Ohno M., Furuichi M., Sakumi K., Nakabeppu Y