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Role of chondrocytes in cartilage formation, progression of osteoarthritis and cartilage regeneration

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In addition to key roles in folate metabolism, dihydrofolate reductase (DHFR) can recycle BH2, and thus regenerate BH4 [1,2]

demonstrated that the absence of FMRP ameliorates Syn-induced DA dysfunction, and suggest that the early loss of FMRP in PD may in fact protective effects in PD