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Efficacy is

All primers used in this study are listed in Supplementary Table S1

In the gastrointestinal tract, it protects the mucosa against NSAID, ethanol, and stress damage, as demonstrated by accelerated ulcer healing in rodent models 2

Mechanistic investigations often pair 5-Amino-1MQ treatment with transcriptomic and proteomic analyses to map the downstream signaling changes that accompany NNMT inhibition, establishing a fuller picture of the enzyme's regulatory network

Oxidative stress occurs when there are too many damaging free radicals in the body compared to beneficial antioxidants, meaning the body cannot neutralize them