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The NHS does not prescribe or endorse CJC 1295, ipamorelin, or retatrutide outside of clinical trial settings

[Abstract]2022 Sep;150(3):727-735.e6

Originally developed to reduce excess abdominal fat in individuals with HIV, Tesamorelin has gained popularity for its ability to stimulate the release of growth hormone, which in turn helps reduce visceral fat and improve body composition

Research-peptide forms have no FDA approval, but the trial-grade adverse-event picture is the most informed source for any user evaluating the molecule

This has been demonstrated in multiple studies with rats and swine, where growth hormone levels significantly increased after injections without impacting ACTH and cortisol plasma levels: In pentobarbital anaesthetised rats, ipamorelin released GH with a potency and efficacy comparable to GHRP-6 (ED50 = 80+/-42nmol/kg and Emax = 1545+/-250ng GH/ml vs 115+/-36nmol/kg and 1167+/-120ng GH/ml)

Many protocols favor dosing at night, since that aligns with your largest natural pulse of growth hormone during deep sleep