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The mice were randomly divided into eight groups: control, vehicle, positive control (0.15 g/kg silymarin), glutathione (0.0166 g/kg), Ganoderma lucidum (Gan, 0.0666 g/kg), vitamin C (0.0666 g/kg), and GGV groups at two doses (0.15 g/kg, 0.45 g/kg)

However, lysosomal dysfunction compromises this clearance mechanism, leading to intraneuronal build-up and aggregation of -synuclein 49

For the GSSG assay, the GSH was removed by addition of 2-vinylpyridine to the supernatant for 1 h at 25 C

Histamine and Other Biogenic Amines in Food