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Furthermore, it has been shown that PINK1 mediates Drp1-Ser616 phosphorylation, promotes mitochondrial division and increases mitochondrial density, while simultaneously participating in the regulation of mitochondrial dynamics (Yang et al., 2022), which subsequently results in ATP depletion and a significant decline in mitochondrial mass (Wang and Zhou, 2020)

Key Takeaways Pure creatine is calorie-free and typically doesnt break a fast from a caloric intake perspective