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KD metabolism produces ketone bodies, with BHB activating mitochondrial uncoupling protein-2 (UCP-2), helping modulate inflammation and metabolism [136]

Protein levels of ATP citrate lyase (ACLY) and 3-hydroxy-3-methylglutaryl-CoA synthase (HMGCS1), which are essential enzymes for mevalonate and lipid synthesis, increased in 3D-cultured cells (Fig

It might also interact with diuretics due to its own mild diuretic properties

It works through pathways that encourage protein synthesis, muscle cell growth, and activation of satellite cells, which help rebuild muscle fibers, while also supporting tendon and ligament repair through collagen production

Much of the clinical work with DSIP has been small scale, in specific populations (e.g., chronic insomniac patients, disturbed human sleep), and sometimes with injections in hospital/lab settings

The protein content of samples was measured in triplicates by using the Bradford assay