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To view a copy of this license, visit About this article Cite this article Karlsson, I., Samuelsson, K., Ponting, D

Some of these adverse effects reported were Toxic Epidermal Necrolysis (a rare but life-threatening skin condition characterized by painful blisters and large areas of skin peeling), air embolism, thyroid dysfunction, and liver, kidney, and neurologic toxicity (The dark side of skin lightening- PubMed) With the proliferation of med-spas in an unregulated fashion, there is a risk of inadequately trained or untrained people giving IV injections in a non-sterile way, which can lead to sepsis and transmission of infections like HIV and hepatitis

Several reports of fungal brain infection [89], Aspergillus abscess resembling a brain tumor [90], spinal cord infection by Aspergillus [91] and fungal granuloma of the brain have been described [92]

Specifically, Ileibacterium valens, Ruminococcaceae, Duncaniella frettoniella, Paramuribaculum, Coriobacteriaceae, Marmorella UCG_002 and Olsenella were identified as characteristic strains associated with NAFLD

The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4

10.1016/j.jff.2015.06.023 39 LivakK