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for instance, CYP1A1 and CYP1A2 induced by TCDD were shown to be protective in Cyp1a1/1a2 double-knockout mice, revealing the complexity of the AhR signaling pathway ( The molecular basis for this functional duality remains to be fully elucidated

Glucocorticoids remain the guideline-recommended standard of care for selected patients

[DOI] [PubMed] [Google Scholar] 116.Ghosh S., Khazaei M., Moien-Afshari F., Ang L.S., Granville D.J., Verchere C.B., Dunn S.R., McCue P., Mizisin A., Sharma K., et al