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Espino et al., 2019

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This concept, known as the entourage effect, suggests that terpenes can enhance or modulate the actions of cannabinoids, improving therapeutic efficacy (Andr et al

Zappasodi R, Serganova I, Cohen IJ, Maeda M, Shindo M, Senbabaoglu Y, et al

Furthermore, evidence from multi-omics studies (Shakt et al., 2024), and the vascular depression hypothesis ( The interaction mechanism between AS and depression is highly complex, involving multiple potential mechanisms, including inflammation (Paranthaman et al., 2012), immune responses (Mousa et al., 2022), autonomic nervous system dysfunction (Pizzi et al., 2010), and intestinal flora and metabolite dysfunction (Wang A

How to think about drugs and supplements as part of a longevity toolkit [1:02:00]