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FADS inactivates tumor-intrinsic cGAS-STING pathway to impede CD8 + T cells recruitment To understand how FADS disrupted chemokine signaling and impaired CD8 + T cell recruitment, we investigated the underlying molecular mechanisms

Abstract Gastric cancer remains a significant global health challenge, with Helicobacter pylori ( H

Acetylation of GR at K494 and K495 weakens its ability to inhibit NF-B, consequently diminishing its anti-inflammatory effect (342)

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Contrastingly, polygenic risk scores, amalgamating the effect sizes of numerous variants into a single score, have shown promise in stratifying individuals with and without epilepsy, demonstrating the potential reliability of PRS-based predictions for clinical applications (Khera et al., 2018)