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Alternatively, arginine is catabolized to ornithine and subsequently to polyamines, which support the synthetic phenotype characteristic of atherosclerotic lesions [38]

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This process is characterized by the binding of monovalent copper (Cu + ) to fatty acylated mitochondrial proteins, promoting their oligomerization and depleting iron-sulfur (Fe-S) cluster proteins and ultimately causing copper poisoning cell death [183]

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10.1016/j.ijpharm.2014.03.017 189 ZhifangC.HeZ

Combined Metabolic Activators with NAD+ and glutathione precursors improved neurological outcomes by a lot in Alzheimer's and Parkinson's animal studies