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Ning B, Zhang Q, Wang N, Deng M, Fang Y (2019) -Asarone Regulates ER Stress and autophagy via inhibition of the PERK/CHOP/Bcl-2/Beclin-1 pathway in 6-OHDA-induced Parkinsonian rats

doi: 10.1016/S0021-9258(19)40958-7

Although the above studies have shown that SGLT2 inhibitors suppress ferroptosis through glucose-lowering independent mechanisms, clinical trials have only observed delayed progression of kidney disease, without confirming direct regulation of ferroptosis markers