l-carnitine and sertraline Carnitine Synergy (D) – Mark Hyman, MD Mitochondria function & Energy I

B., Henry, G., Thierry, A., & Gagnaire, V

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Shanxi Provincial Administration of Traditional Chinese Medicine (2023ZYYC2034), Science and technology innovation project of higher education in Shanxi Province (2020L0204, 2022L132)

10.5897/JMPR2014.5681 65

L-carnitine (the parent compound) displays immunosuppressive properties and abrogates intestinal inflammation in experimental colitis models by inhibiting both APC and CD4+ T cell function.[18] ALC has been shown to increase the ratio of Treg cells in colon while decreasing the ratio of Th17 cells and macrophages, thereby improving immune tolerance.[2] Combination Strategies for Systemic Inflammation: ALC 1,500-2,000 mg/day + Omega-3 fatty acids 2-4 g/day + Curcumin 500-1,000 mg/day + Vitamin D ESTIMATED COSTS Acetyl-L-Carnitine (Generic): 500 mg capsules: $0.20-$0.50 per capsule Daily cost (1,500 mg/day): $0.60-$1.50/day ($220-$550/year) Daily cost (3,000 mg/day): $1.20-$3.00/day ($440-$1,095/year) Brand Name Products: Varies by manufacturer

& Seeburg, P