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Although, CVB infection may prime T cells to cross-react against a protein sequence that mimics a self-antigen, AAb are not causative and have mostly been used as biomarkers ( Moreover, CVB was shown to persistently infect a human pancreatic ductal cell line (147)

AhmadianMAbbottMTangTHudakCKimYBrussMet alDesnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype

However, additional experimental validation is needed for the particular metabolites implicated, their target molecules, and the upstream and downstream pathways in TC