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Description

288 Notably, clustered regularly interspaced short palindromic repeats (CRISPR)-Cas is currently recognized as one of the most powerful gene-editing tools available

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Because the active (non-protonated) Meta II conformation absorbs at 378 nm, it appears that most of the chromophore in the triple mutant is bound via a non-protonated Schiff-based linkage

A., Ito, T., Michlek, M., Sugimoto, S., Kita, H., Chijimatsu, R., Ukon, Y., Kushioka, J., Okada, R., Kamatani, T., Hashimoto, K., Tateiwa, D., Tsukazaki, H., Nakagawa, S., Takenaka, S., Makino, T., Sakai, Y., Necas, D., Kaito, T