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10.1016/j.cmet.2020.01.001 283 ZaheerM.ChrysostomouP.PapademetriouV

IV therapy is excellent for rapid or intensive support but should be supervised by a professional

This is because chemotherapy drugs such as bortezomib generate high concentrations of ROS, which is a key factor in the induction of mitochondrial dysfunction, microtubule damage, demyelination, and cell apoptosis, leading to neuronal damage [16]