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Iron as a redox-active metal has the ability to produce ROS, not only via the Fenton reaction but also through REDOX reactions occurring during the conversion between Fe 3+ and Fe 2+ (Thvenod, 2018)

UVB irradiation commonly induces oxidative stress, DNA damage, and inflammation 6 , leading to various skin issues such as loss of elasticity, laxity, roughness, thickness, deep wrinkles, and irregular pigmentation, as well as severe conditions like skin cancer 1

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Specifically, the following key terms were used to generate the literature search for this review paper: Menopause, oxidative stress, antioxidants, estrogen, free radicals, herbal antioxidants, pharmacotherapy, hormonal therapy, phytoestrogens, osteoporosis, cardiovascular disease, and vasomotor disturbances