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The authors have investigated three treatments to correct metabolic abnormalities which have demonstrated improvement in behavior and/or metabolism, namely the combination of methylcobalamin (mB12) with low-dose folinic acid (LDFA) to treat oxidative stress in an open-label study (James et al., 1A demonstrates where these agents are believed to act within four major interconnected metabolic pathways that are known to be disrupted in ASD

Santello et al., 2011)

Shi, X., de 637 Rezende, J

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During high levels of release, serotonin spills over to reach extra-synaptic receptor sites in the initial axon segment of motoneurons, inhibiting action potential generation (Cotel et al

Yanez, JoAnn