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Description

Niemann B, Rohrbach S, Miller MR, Newby DE, Fuster V, Kovacic JC

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Melanotan I (afamelanotide) is a lab-made version of a natural skin-pigment hormone that tells your skin cells to produce more melanin, the pigment that darkens skin

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The highest score of 10 points reflects the greatest impairment, while the lowest score of 0 points represents normal forelimb function

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any dose changes should involve a clinician

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TNF-, IL-1, and IL-6 levels were quantified using commercial ELISA kits (Invitrogen) following manufacturer protocols

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Carlsson 2018 - body-weight exposure covariate

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