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10.1155/2015/423490 10 AlhaithloulH

Our experiments in mouse models of mild hyperhomocysteinemia caused by a deficiency in cystathionine beta-synthase in CBS +/ (heterozygous deficient) mice found that increased plasma total homocysteine caused abnormal responses to endothelium-dependent vasodilators

In contrast to other neurodegenerative diseases such as Alzheimers and Huntingtons diseases (AD and HD), many of the characteristics of PD can be reproduced in vivo by the use of specific neurotoxins

Likewise, in male silk moth ( Bombyx mori ), the antennae specific BmGSTD4 had high GSH-conjugating activity towards 1-chloro-2, 4-dinitrobenzene (CDNB), indicating its potential role in the metabolism of xenobiotics [108]

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527 Currently, the drug is in Phase II clinical recruitment to compare the safety and efficacy of three different doses in patients with nAMD (NCT05637255)