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Efflux transporters expressed at the BBB limit the brain access of such drugs, which are substrates of these transporters

Aoyama M, Kawase H, Bando YK, Monji A, Murohara T (2016) Dipeptidyl peptidase 4 inhibition alleviates shortage of circulating glucagon-like peptide-1 in heart failure and mitigates myocardial remodeling and apoptosis via the exchange protein directly activated by cyclic AMP 1/Ras-related protein 1 axis

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10.1016/S0092-8674(00)80493-6

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