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Ketone bodies not only serve as alternative energy sources but also activate the Nrf2 pathway to reduce oxidative stress, thereby protecting neurons from damage (29, 3335)

The depletion of glutathione may further worsen symptoms and contribute to oxidative damage

This groups nerve cross-sections revealed several freshly regenerated tiny axons with a very thin myelin sheath and small diameter

Protein concentration was determined by the Bradford assay using the Bio-Rad Protein Assay Kit (Bio-Rad)

Its occurrence and progression are associated with the accumulation of driver genetic mutations that provide a selective growth advantage to cells 15,16

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