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Like normal HSCs, LSCs reside in the BM niche of AML patients (23) which supports their survival and protects them against chemotherapeutic drug treatment (2426)

Shacter E, Williams JA, Lim M, Levine RL (1994) Differential susceptibility of plasma proteins to oxidative modification: examination by western blot immunoassay

Moreover, we identified four species, ( Xestospongia bergquistia , Nematostella vectensis , Ciona intestinalis , and Branchiostoma floridae ) that do not have any peroxisomal CAT but instead encode a cytoplasmic CAT (Fig

Indeed, the W34A mutation, which disrupts the ability of WW domain bind to a pSer/Thr-Pro motif 44 , prevented the PIN1 interaction with CDH1-WT (Supplementary Fig

doi: 10.1016/j.jcin.2015.07.021 3

TB-500 exerts its primary effects through upregulation of actin, the cytoskeletal protein critical to cell structure and motility