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While it may help increase natural testosterone in men with obesity-related low T, men with primary hypogonadism or clinically documented testosterone deficiency still require TRT for adequate hormone restoration

Drug design, development and therapy 13:13351345 Lim KM, Bae S, Koo JE, Kim ES, Bae ON, Lee JY (2015) Suppression of skin inflammation in keratinocytes and acute/chronic disease models by caffeic acid phenethyl ester

Despite these efforts, the technique still suffers from limited depth sensitivity, which is crucial for instance in measurements of the cerebral hemodynamics, limiting its translation to the clinics

doi: 10.1186/s13148-021-01198-z

Direct 9 , e1433 (2023)

Accepted : 17 December 2020