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This represents one of the most critical intrinsic factors, rather than mobile genetic elements, associated with antibiotic resistance, usually resulting from their overexpression

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Led by Leanne Li at The Francis Crick Institute, the InteroCANCEption team wants to know if the brain can also sense a tumour in the same way, by picking up small signals from inside the body through the nervous system If we can understand the bodys internal alarm system, we can drive meaningful advances in our understanding of neuroimmune interactions, with the ultimate aim of developing innovative therapies that target the nervous system and expand what is possible in cancer treatment

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After 6 h of OGD, both exogenous and mutant TIGAR failed to rescue NADPH loss in cells, reproducing the PPP deficiency observed in ischemic mouse brains, but both wild-type and mutant TIGAR significantly reversed ROS burst in cells (Liu et al., 2022)

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