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Formerly known as manic-depressive illness, this disorder involves episodes of depression and mania (extremely high energy and elevated mood)

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BM-MSCs transplantation could benefit mitochondrial and induce mitochondrial transfer to rescue protect renal TECs, by inhibiting apoptosis and improved morphology, of tubular basement membrane and brush border structure

An important role in this type of apoptosis is played by cytochrome C which is released due to ionic imbalance, mitochondrial swelling, or the formation of a pore in the mitochondrial outer membrane (MOM

Adherence is the key problem!If 70% of the patient discontinue the treatment after 6-12 month and regain the weight very quickly, handling the adherence weakness is much more helpful to the patient's health than another 3% weight loss.Alma's smart capsule we can probably load GLP1 or Amylin on a once / twice weekly oral dose