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In addition, we discuss the discovery of biological targets associated with the BBB to provide a reference for further improvement of epilepsy treatment strategies in the future

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(2013) 1:e23992

GPx isoenzymes are all antioxidant enzymes that reduce potentially damaging reactive oxygen species (ROS), such as hydrogen peroxide and lipid hydroperoxides, to harmless products like water and alcohols by coupling their reduction with the oxidation of glutathione (Figure 2a )

Immunofluorescence analysis further revealed a reduction in mitophagosome formation following PX-478 treatment (Fig

This creates a favorable environment for tumor cells to evade immunosurveillance, promoting tumorigenesis and progression [7]