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As aforementioned, the effects on redox balance favoring more oxidation can reduce the antioxidant capacity in the circulation and damage protective mechanisms

229,230 Interestingly, in a patient with SCO2 mutations who presented with severe hypertrophic cardiomyopathy, Cu-histidine supplementation has been reported to improve heart function, showing attenuated cardiomyopathy as well as the normalization of blood pressure

Dietary vitamin B6 intake modulates colonic inflammation in the IL10(/) model of inflammatory bowel disease

10.1034/j.1600-0838.2001.110606.x 57 HartmanM

Biotin (1 mM in PBS, sterile filtered) was added to a final concentration of 50 M at the indicated timepoint, and cells were fixed and stained 24 h after seeding

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