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However, these observations are in sharp contrast to what Rojano-Ortega (Reference Rojano-Ortega72) concluded in a systematic review of its impact on exercise-induced oxidative stress

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Yang et al., 2018)

J Physiol Biochem 68(1):7790 Babu GN, Kumar A, Singh RL (2011) Chronic pretreatment with acetyl-L-carnitine and DL--lipoic acid protects against acute glutamate-induced neurotoxicity in rat brain by altering mitochondrial function

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In order to maintain the TCA to continue to produce energy in the cell, lactate produced in the muscle during contraction needs to be reduced