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Visualization of predicted binding pockets in the protein structure showing different potential ligand-binding sites: (a) primary binding pocket highlighted in red, (b) secondary surface pockets highlighted in blue, (c) ligand-interacting cavity highlighted in yellow with bound conformation, and (d) another potential internal binding pocket highlighted in yellow within the protein structure Figure 8

doi: 10.1016/j.arth.2025.01.001 19 HongM.WangJ.JinL.LingK

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This is also why you might notice that diets and exercises that worked for you in the past do not work as well or at all later in life

10.1161/STROKEAHA.117.018290 207 WilliamsonM

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