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Overexpression of dFOXO has been shown to protect DA neurons in Drosophila Pink1 -null mutants [161], while other studies have shown that dFOXO-induced apoptosis mediates DA neuron death in Drosophila DJ-1 loss-of-function mutants [162] and dLRRK mutants [163]

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Hydrophobic antioxidants can easily enter the cytoplasm and attenuate ROS formation and accumulation in 6-OHDA toxicity

El envo se realiza por Colissimo en 4 a 5 das laborables, a un punto de recogida cercano (10,90 ) o a su domicilio con firma (12,90 )

LC3-II, Membrane-bound form of microtubule-associated protein 1A/1B-light chain 3

doi: 10.1016/j.vph.2022.106976 16 JoshiSRKitagawaAJacobCHashimotoRDhagiaVRameshAet al