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Fe 2+ induced iron accumulation, oxidative damage and autofluorescence of photoreceptors, resulting in photoreceptor death and RPE autofluorescence in mouse models (Shu et al., 2020)

Subnormothermic machine perfusion (SMP) and controlled oxygenated rewarming (COR) were experienced in animal models demonstrating the improvement in renal or liver function and superiority when compared to SCS 15,16,17 , but to present only COR in LT was applied in clinical practice with good results of feasibility and short-term transplant outcomes 18

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