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Separation of the tryptic peptides was achieved at 60 C column temperature with the following gradient of water/0.1% formic acid (solvent A) and acetonitrile/0.1% formic acid (solvent B) at a flow rate of 400 nL/min: Linear increase from 2% B to 17% B within 18 min, followed by a linear gradient to 25% B within 9 min and linear increase to 37% solvent B in additional 3 min

presented a case report from July 2020 describing a severely ill 74-year-old, COVID-19-positive woman with ARDS and sepsis who, after receiving 11 g/day of IV vitamin C, showed marked improvement in her oxygen saturation and was subsequently extubated three days later [57]

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