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However, IBN mice exhibited markedly impaired oligodendrocyte regeneration and remyelination compared to control mice in the presence of interferon (IFN-) ( + mice developed much more severe EAE because oligodendrocytes from these mice were more vulnerable to inflammation than those from control mice ( Oligo ) showed a decrease in the loss of mature oligodendrocytes, which in turn prevented demyelination upon EAE challenge ( Oligo mice was more dependent on controlling oligodendrocytes themselves, while the change in inflammation was not significant

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Colombian parasites clustered with some populations present in Venezuela and Honduras, while the ones from Ecuador and Loreto were related

Mechanistically, lycopene functions through both physical and chemical quenching of reactive species (122124)

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Clin Chim Acta 325(12):165170