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-mangostin promotes apoptosis of human rheumatoid arthritis fibroblast-like synoviocytes by reactive oxygen species-dependent activation of ERK1/2 mitogen-activated protein kinase

Toxicol Appl Pharmacol 207(2):179186 International Transporter, Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL et al (2010) Membrane transporters in drug development

The strains were inoculated into LB liquid medium containing ampicillin (100 g/mL, TaKaRa Biotechnology (Dalian) Co., Dalian, China) and cultured at 37C with a shaking speed of 150 rpm until the optical density (OD) reached approximately 0.6

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Deep sequencing indicated that miR-21-5p and/or miR-NC are involved in this phenomenon ( Figure 4C )