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Reversible myelopathy in a 34-year-old man with vitamin B12 deficiency

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Beyond delivering MSCs and cytokines to suppress inflammation, subchondral BMAC injection may exert therapeutic effects through local decompression, counteracting the high-pressure microenvironment within BMLs

Covalent and noncovalent intermediates of an NAD utilizing enzyme, human CD38

All dosing is speculative because rat studies used intraperitoneal administration that doesnt directly translate to human routes

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