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Pre-clinical work across skin, lung, liver, and bone models has reported tissue-repair activity, attributed to fibroblast restoration, antioxidant signaling, anti-inflammatory effects, and matrix-protein synthesis

Conditions that interfere with nutrient absorption, such as celiac disease or Crohn's disease, can cause B 12 trouble

While it is important to note that most evidence remains preclinical, the breadth and consistency of findings across different research models provides a strong foundation for understanding the compound therapeutic potential

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In addition to these intracellular inflammatory events, the integrity of the bloodbrain barrier (BBB) plays a decisive role in shaping the neuroinflammatory environment in PD [53]