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This recomposition is the GH effect at work: it selectively preserves lean mass while mobilizing fat

The cost typically ranges from $200 to $500 per month depending on the clinic and dosing protocol

The primary underlying pathomechanism is most likely a decreased hepatic GHR expression related to insulin deficiency, resulting in GH-resistance and impaired hepatic IGF-1 synthesis, which stimulates pituitary GH-secretion by a feedback mechanism [188, 189]

But it does so in an episodic manner