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Researchers can introduce specific gene mutations into Drosophila or manipulate gene expression to observe the resulting phenotypes

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Acknowledgements Authorship All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this article, take responsibility for the integrity of the work as a whole, and have given their approval for this version to be published

Research suggests FOXO4-DRI targets senescent cells by disrupting the FOXO4p53 interaction, allowing damaged cells to undergo apoptosis

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