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Its preclinical biology is genuinely interesting

DOI: 10.1113/jphysiol.1934.sp003147 Gericke A et al (2011): Role of M1, M3, and M5 muscarinic acetylcholine receptors in cholinergic dilation of small arteries studied with gene-targeted mice

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CerS2 exhibits activity toward the very long acyl CoAs such as C22C24

If you've been consistent for 8 weeks with no noticeable difference, check in with your doctor rather than simply increasing the dose

Its also possible that the relaxation and stillness required during the infusion process contribute to a sense of sleepiness post-treatment, as the body may take this as an opportunity to rest